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Fatty Acids Corrupt Neutrophils in Cancer
Understanding how tumors escape from immune attack may offer novel therapeutic opportunities. Veglia et?al. (2019) demonstrate in Nature that fatty acid transport protein 2 (FATP2) endows neutrophils with immunosuppressive capabilities that promote cancer growth. This receptor can be targeted to unleash anti-tumor immunity and to potentiate immune checkpoint blockade.
pmid: 31185209 Cancer Cell 影響因子: 23.916 發表日期: 20190610 官網 免費下載
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